Sponsored link. Recapping information in this section of stem cells:. In late , a technique was proven in principle that can reprogram adult stem cells so that they have many of the same properties and potential of embryonic stem cells. This may completely revolutionize future research techniques, allow government research funding to be increased, and offer hope to the approximately million Americans who suffer from a wide range of debilitating diseases and disorders that may eventually be treated or cured with stem cells. In JUN, a medical research group led by Dr.
New steps forward in cell reprogramming
Reprogrammed Pluripotent Stem Cells from Somatic Cells
By Lawrence S. Goldstein, Meg Schneider. Stem cells can renew themselves a process called self-renewal , and they can also make a variety of other kinds of cells. Stem cells are either embryonic stem cells or adult stem cells. In the body, these cells eventually disappear, so a human adult body no longer contains cells that can generate any kind of cell — at least not in the normal course of things.
Reprogramming adult cells into induced pluripotency with unprecedented efficiency
Pluripotent stem cells, such as embryonic stem ES cells, can differentiate into all cell types. So, these cells can be a biological resource for regenerative medicine. However, ES cells known as standard pluripotent cells have problem to be used for cell therapy because of ethical issue of the origin and immune response on the graft. Hence, recently reprogrammed pluripotent cells have been suggested as an alternative source for regenerative medicine. Somatic cells can acquire the ES cell-like pluripotency by transferring somatic cell nuclei into oocytes, by cell fusion with pluripotent cells.
The results have been published in the journal Cell Cycle. Stem cells are specialized, undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, they serve as a sort of internal repair system in many tissues, dividing essentially without limit to replenish other cells. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another a more specialized cell type, such as a muscle cell, a red blood cell, or a brain cell Fig 1.