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Plant cells are covered with rigid cell walls, yet tip-growing cells can elongate by providing new cell wall material to their apical regions. These experiments, however, do not address how living tip-growing cells react when they encounter physical obstacles that are not substantially altered by turgor pressure. The cells were grown inside microfluidic chambers and guided towards the gaps using microdevices customized for each cell type. All types of tip-growing cells could grow through the microgaps with their organelles intact, even though the gaps were much smaller than the cylindrical cell diameter. Our findings reveal the dramatic physiological and developmental flexibility of tip-growing plant cells. The microfluidic platforms designed in this study provide novel tools for the elucidation of the mechanical properties of tip-growing plant cells in extremely small spaces.
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By Tansey Tang. Has sex been painful during penetration? The condition, known as vaginismus, is not as uncommon as you might think. The harder you try, the more anxious you get, making things worse. What are you doing wrong?
I fear that I am grossly misinformed about my body and perhaps the female anatomy in general, but alas, I think I'll ask my question anyway. At the age of 19, I've decided that it's time for me to penetrate my vagina, but for some reason, I can't get the little bugger open! I've been following your instructions--playing with myself, taking my time, exploring my nether regions--but it hasn't been working. As you can imagine, this is seriously frustrating! I've been actively trying to penetrate my vagina for about two months now, and I can only get one finger in.